According to the data provided by the Synapse Database, As of December 4, 2024, there are 73 investigational drugs for the GIPR x GLP-1R target, including 37 indications, 66 R&D institutions involved, with related clinical trials reaching 298, and as many as 1883 patents
Anderson JM, Van Itallie CM
This article analyzes the costs and benefits of health plan coverage of GLP-1s
One interesting trial was conducted using high dose melatonin as a radioprotector in a phase II radiation therapy oncology group trial in patients with brain metastases [51]
Moreover, this class of drug is also contraindicated in patients with hypersensitivity to GLP-1R agonists, pancreatic cancer, or a history of pancreatitis [87]
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